Gene editing technology allows to introduce and correct disease-linked mitochondrial DNA mutations in liver and skin cells In a step toward treating mitochondrial diseases, researchers in the ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

The aging process is influenced by several factors, including the accumulation of mutations and the acquisition of epigenetic alterations throughout life. A recent study by Koch and colleagues ...

The prothrombin gene mutation increases your risk of severe blood clots. Medications, regular checkups, and healthy lifestyle habits can help reduce this risk. The prothrombin gene plays a crucial ...

Aging is a critical risk factor for cancer development with genetic instability presenting as a common hallmark. Alternative DNA-forming sequences are endogenous sources of genetic instability that ...