The Collection “DNA Replication and Replication Stress” brings together original research articles, critical reviews, and perspectives from scientists with diverse viewpoints and areas of expertise in ...

Segmental copy-number gains are major contributors to human genetic variation and disease, but how these alterations arise remains incompletely understood. Here, based on the analyses of both ...

When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two papers ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...