Neuroscientists have been trying for decades to understand how the brains of humans and other animals develop throughout the lifespan. While their work has gathered much insight into brain maturation ...

A brain structure called the amygdala, and its connections with another region, the prefrontal cortex, shape people’s experiences and social interactions. The discovery of a key molecular mechanism ...

This schematic outlines their analytical framework. The approach involves creating a validated developmental atlas of the dorsal prefrontal cortex from structural connectivity, then using these ...

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...

Quantitative assessment of prefrontal cortex in humans relative to nonhuman primates. Proc Natl Acad Sci U S A. 2018 May 29;115 (22):E5183-E5192. doi: 10.1073/pnas.1721653115.

The prefrontal cortex occupies the anterior portion of the frontal lobes and underpins a spectrum of cognitive processes including planning, decision-making, working memory and inhibitory control, ...

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to ...

During adolescence, the teen brain goes through dramatic changes which scientists are just beginning to better understand. For parents, teachers, and anyone who cares for a teenager—it is often ...

As I gradually cross the threshold from adolescence to adulthood, I often hear my peers joke that their prefrontal cortex is developing when they find themselves happily going to bed early on a Friday ...