A core challenge in biology is understanding how processes in the body, such as cellular development and regeneration, unfold ...
A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into ...
In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions ...
A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...
Glioblastoma kills most patients within 15 months of diagnosis. It is the most aggressive brain cancer in young adults, and ...
With global life expectancy steadily increasing, the growing gap between lifespan and healthspan has placed the aging of the ...
The bird retina is one of the most energetically expensive tissues in the animal kingdom, yet it doesn’t use the energy advantage of oxygen. New research finally explains how this is possible.
A team led by Cedars-Sinai Health Sciences University investigators has created a faster, cheaper way to determine the genes expressed in cancerous tumors. The AI-based tool, which they describe in ...
Abstract: Spatial transcriptomics (ST) are emerging technologies that reveal spatial distributions of gene expressions within tissues, serving as important ways to uncover biological insights. However ...
Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy characterized by marked cellular and spatial diversity within the tumor microenvironment (TME). The transforming growth factor-β ...
The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...
Do you want to generate spatial transcriptomics data using your H&E images? We introduce DeepSpot, a novel deep-learning model that predicts spatial transcriptomics from H&E images. DeepSpot employs a ...